levinlab.dev/Hypothetical Herald
Hypothetical Article
Score out of 10
Polygenic Risk for Morphogenetic Dysregulation and Bioelectrical Responses to Growth-Promoting and Growth-Inhibiting Cues in Young Donor-Derived Organoids
6.7
Structural determinants of Dishevelled isoform selectivity at the Wnt receptor Frizzled-7
7.3
Bioenergetic Coupling to Transcriptional States Shapes Cooperative Regeneration
6.7
Epigenetic pattern memory increasingly guides appendage regeneration as bioelectric cue sensitivity wanes with ontogenetic maturation
7.0
Bioelectric remodeling of the blastemal signaling center after cyclic mechano-stimulation during appendage regeneration
6.3
Glycogen supports glycolytic plasticity in morphogenetic blastemal cells
7.3
Matrix-over-morphogen effect depends on interaction between progenitor lineage history and mechano-chemical integration: An examination using standardized decellularized scaffold cultures
6.3
Recent Advancements in the Regenerative Management of Age-Related Dermal Degeneration
6.7
Power-law scaling of bioelectric morphodynamic activity demarcates limb bud compartments
6.3
Phantom Positional Signals Modulate Canonical Patterning Versus Experimental Regeneration Pathways: A Longitudinal Analysis in Multicellular Organoids
6.0
Chemical flavorants differentially modulate appendage regenerative capacity in a juvenile vertebrate immersion model
6.0
Uncovering morphogenetic control strategies with compact recurrent gene-circuit models
7.0
Context-dependent fidelity of damage-induced cytokine bursts across vertebrate regeneration models
6.3
Latent herpesviruses correlate with steeper age-related escalation of circulating fibrosis- and senescence-associated biomarkers in phenotypically normal women
6.0
Sequencing of morphogenetic modules in the central apical ectodermal ridge
6.3
Optogenetic Modulation of FGF-Secreting Organizer Cells Alters Trajectory Bias and Pattern Encoding in the Limb-Bud Progress Zone during Gradient Conditioning
7.0
The temporal context of cytoneme-mediated contacts governs the interpretation of inductive cues during lineage specification
6.3
Mapping the evidence base for non-prescription phytocompounds, nutraceuticals and repurposed agents assessed for promoting adult tissue regeneration: a scoping review
5.7
CALCA-positive sub-blastemal niche cells delineate a mesenchymal-epithelial axis for aversive wound signalling
6.0
ADAPTER: A Conceptual Framework of Axial-Domain-Guided Pattern Recall during Morphogenesis
6.3
The MDM2–p53 module modulates Wnt-Fzd4 signaling and epithelial barrier assembly
7.3
Differential paracrine sensing in limb-bud progenitors: influence of tissue relatedness and morphogenetic context
6.3
MRG-H: A hierarchical framework for autonomous tissue regeneration via transcriptome-conditioned morphogenetic learning
6.7
Risk of morphogenetic drift following systemic administration of an α2δ-ligand in adults with lumbar mesodermal degeneration
5.0
Boosting FGF-2 in post-injury regenerative lag: Topical fibroblast growth factor enhances stromal anabolic tone and paracrine support for progenitor cells
6.0
“There is just too much going on there”: Integrative challenges of noncanonical intercellular signalling in bioelectrically divergent tissue domains
5.0
Multidomain morphogen processing in limb bud signaling centers implements inverse morphogenesis
6.0
Assessing early-stage teratogenic exposure using the Embryonic Pattern Checklist
6.7
Postmortem p16INK4a-positive senescent cell burden in zone II articular cartilage of older adult males with a history of youth high-impact athletics
6.3
Occluding Apical or Basal Signalling Interfaces of Organizer‐Like Cells Does Not Hinder Lineage Specification in Human Gastruloid Models
6.7
Genetic and environmental determinants of wound epithelium consolidation, blastema anchoring, and pro-inflammatory signal persistence at 2 and 5 days post-amputation: a longitudinal clonal amphibian study
6.0
Divergent paracrine dynamics originate parallel morphogenetic programs during appendage regeneration
7.0
Up for Debate: Does Routine Mechanobiological Stimulation Truly Enhance Regenerative Capacity?
6.0
Morphogenetic event structure sculpts stem-cell population dynamics in the lateral epithelial compartment
7.0
Temporal modulation of nephron progenitor competence orchestrates epithelial maturation during murine kidney development
7.7
Re-epithelialization of chronic cutaneous ulcers with directly induced epithelial stem cells
7.0
Genetic and microenvironmental determinants of epithelial quiescence, junctional stabilisation, and cytokine-burst duration at 2- and 5-day stages of human organoid maturation: a longitudinal clonal study
6.3
Impact of limb regenerative asymmetry on systemic patterning outcomes: a systematic review
6.0
Periportal hepatic stellate cells govern morphogenetic adaptability and systemic metabolic homeostasis in mouse models
6.0
A meta-analytic review of early inflammatory exposure and intrinsic mechanochemical sensing
6.3
Sensorial epithelial cell degeneration drives homeostatic junctional remodeling of regenerative blastema cells
6.0
Delayed nutrient delivery relative to an individual regenerative phase is linked to reduced progenitor responsiveness and shaped by inherited factors
5.7
Gestational and Lactational Exposure to Perfluorohexanoic Acid Compromises Skeletal Muscle Regeneration in Adult Male Mice: A Preliminary Study
6.3
Long-term enhancement of limb regenerative fidelity after a single bioelectric reprogramming pulse in fibrotic mammalian tissue
6.0
Potential role of embryonic haemodynamic experience in the emergence of the arterial–venous dichotomy
6.3
Identification of proliferating cardiogenic progenitors in the adult human ventricular subepicardial niche
6.7
Synthetic mRNA nanotherapy for recessive morphogenetic deficit 9: a single-cohort regenerative study
6.0
Digital propagation of regenerative myths skews induced blastema therapy literacy, ethical appraisal, and participation intent
6.3
A glycogenolytic switch preserves epithelial morphogenesis from proteotoxic disruption
7.0
Acute and sustained reorganization of human epithelial regenerative circuits by an indole-alkaloid bioelectric modulator: a precision morphogenetic imaging trial
6.7
Programmable somitic-oscillator gene circuits for autonomous phase-specific delivery of regenerative morphogens
6.7
Head-to-head comparison of two collagen-specific PET/CT tracers, [18F]D3Col ([18F]R16-129) and [18F]Col45, for in-vivo quantification of post-infarct myocardial remodeling
6.3
Digital disinformation disrupts regeneration: impacts of micro-video narratives on pluripotent stem-cell therapy literacy, bioethical concern, and enrollment intentions
6.7
Triglycerides are an essential fuel reserve for gap-junction dynamics during epithelial regeneration
7.3
A unified framework to model gap-junctional dynamics across the growth–quiescence cycle
5.7
Bioelectric Burst Characteristics and Coupling within the Somatic Epithelium–Blastema Circuit Dynamically Relate to Regenerative Stalling during Adult Limb Repair
6.3
A unified framework to model gap-junction dynamics during the growth–quiescence cycle
6.0
Ultraweak photon emissions as optical markers of morphogenetic tissue dynamics
5.7
Distinct pattern memory rules govern apical and basal membrane compartments in vivo during tissue remodeling
7.0
Re-enchanting organizer cells through lexical changes
4.7
Decoding combinatorial morphogen-bioelectric inputs: compartment-specific mechanisms of positional code interpretation in congenitally gradient-deficient and intact embryos
6.7
PTEN in somatostatin-positive stromal progenitors modulates fibrotic stress and is required for inhibitory gap-junction coupling within the limb blastema
5.7
Fine-mapping genomic loci refines craniofacial malformation risk genes
6.7
Aberrant inhibitory morphogen decoding in the apical ectodermal ridge of regenerated limbs with recurrent patterning defects
6.3
Systematic Umbrella Review and Meta-Meta-Analysis: Efficacy of Cyclic Biomechanical Loading in Normalising Pattern Formation and Stress-Response Set-Points During Juvenile Development
6.7
Reduced posterior-to-anterior bioelectrical coupling for dynamic tissue homeostasis in late middle-to-older organisms
5.7
Advances in magnetic resonance imaging of embryonic tissue morphogenesis and its applications in pediatric regenerative medicine
6.7
Probing morphodynamic truth: an exploratory cross-sectional analysis of cytoskeletal modulation symptoms and protrusion behaviour in a juvenile epithelial cohort
5.0
Decellularized Matrix Sheets versus Micro-Patterned Synthetic Films: Divergent Re-Engagement of Positional Gene Networks During Limb Regeneration
6.3
Basal bioelectric oscillations in quiescent epithelium forecast intrinsic regenerative restraint
5.7
High-throughput multiplex bioelectric clamp profiling of acutely isolated blastemal progenitors
7.3
Preferred leftward recumbency highlights lateralized bioelectric patterning in domestic cats
3.3
Closed-loop bioelectric modulation prevents progressive morphogenetic dysregulation and preserves regenerative pattern fidelity
6.7
Disentangling progressive regenerative decline from fixed developmental baselines using cross-sectional morphogenomic profiling
7.0
MeSiFuN: A toolbox to map mesenchymal signaling networks in developing human tissues
7.3
Large-scale high-density tissue-wide bioelectric recording in nonhuman primates
5.3
Quantum‐coherent microtubules as a substrate for organismal pattern memory resolve the integration and causal sufficiency challenges
4.0
Pro-regenerative mechanical-loading responses in the satellite-cell niche of a dystrophic mouse model revealed with single-nucleus RNA sequencing
7.3
Spatial gating and Noelin-mediated clustering of native Ca2+-permeable morphogenetic ion channels
7.7
Unsupervised prepatterning in multicellular morphogenetic circuits
7.0
Retinoic-acid modulation of epithelial bioelectric networks supports sequential and complementary roles for quiescent and growth phases in pattern-memory consolidation
6.3
Opposite regulation of epithelial relay cell excitability during acute regenerative response versus chronic non-healing injury
6.3
Physiological homeostasis and pattern memory: testing bidirectional associations in the Zebrafish Lifespan Regeneration Atlas (ZLRA)
6.3
Uncovering injury-specific proteomic signatures and regenerative decline risks in single and repetitive appendage trauma
7.3
Tissue damage signals dynamically modulate apical epithelial autophagy to gate regeneration onset
7.0
Cancer research needs developmental biology and developmental biologists
6.0
Stellate stromal cells may underpin the body’s massive pattern-memory capacity
6.0
Tissue-level mechanisms underlying the inhibitory control of pattern memory during regeneration
6.3
Blastemal Depolarization Microbursts Decline during Contractile Episodes and Substrate Uptake in Immobilized Limb Buds
6.3
Inferring patterning states across murine and primate epithelial organoids using cell-surface morphometrics
7.0
Tissue-resident macrophage activation orchestrates CXCL10-mediated CD8⁺ T-cell recruitment to drive ageing-related loss of skeletal muscle regenerative capacity
7.7
The transcriptomes, intercellular coupling and ontogeny of submucosal stromal lineages in the mouse small intestine
7.3
Persistent Fibrosis Linked to Bioelectric Overactivity in the Blastema Organizer
6.3
World first: bioelectric implant enables patient-directed tissue patterning with nuanced gradient modulation — and tri-tone myofiber orchestration
5.7
How embryonic tissues discriminate authentic morphogen gradients from self-generated pattern cues
6.3
Vesicular heat-shock proteins orchestrate an epithelial-sheath unfolded-protein-response circuit that buffers sensory ageing in Caenorhabditis elegans
7.3
Spatially-resolved Fzd1- and Fzd2-governed fibroblast signaling axes differentially gate regenerative versus fibrotic dermal repair
7.3
Chronic Systemic Hyponatremia Potentiates Aberrant Regenerative Patterning Through Dysregulation of Biogenic Amine-Driven Morphogenetic Signaling in Mice
6.7
Directing fibrotic versus regenerative outcomes through parallel genetically-distinct basal mesodermal pathways to distal blastema subregions
6.3
Chronic Hyponatremia Potentiates Innate Morphogenetic Mispatterning Through Dysfunction of Indolamine- and Catechol-Signaling Progenitors in Murine Limb Buds
6.0
A volatile morphogen directly activates RyR1 to regulate epimorphic regeneration in vertebrates
6.7
Nutrient scarcity modulates the link between intestinal symbiont consortia and risk of regenerative compromise in adults
5.7
Quiescent–remodeling cycles sculpt long-term pattern memory during regeneration
7.3
Tuning regenerative activation
7.0
Wnt/β-catenin says shape that again
7.0
Chronological drift of morphogenetic circuits displaces RNA-processing hubs and triggers unrestrained stress signalling in regeneratively exhausted neural tissue
6.3
Senescent morphogenetic fields redirect spliceosomal modules and compromise tissue‐level stress resilience
6.0